APE1 (APEX1) Mouse Monoclonal Antibody [Clone ID: 2104]

CAT#: AM06005PU-N

APE1 (APEX1) mouse monoclonal antibody, clone 2104, Purified

Product Images

Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 2104
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 20 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Full length human APE1 purified from E. coli.
• Specificity: This antibody detects APEX Nuclease (multifunctional DNA Repair Enzyme) (APEX) (APEX1).
• Formulation: PBS, pH 7.2 without preservatives
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein G Chromatography
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 328 Human
• Background: Apurinic / Apyrimidinic Endonuclease (APE 1 or REF 1) is responsible for the incision of DNA at abasicsites during base excision repair. It has also been shown to stimulate the sequence-specific DNA binding activity of Fos-Jun (AP 1) heterodimers. Alterations in APE 1 levels have been described insome cancers.
• Synonyms: APE, APEX, APX, HAP1, REF1, APEN