Glutathione Peroxidase 7 (GPX7) Mouse Monoclonal Antibody [Clone ID: 2704]
CAT#: AM06045PU-N
Glutathione Peroxidase 7 (GPX7) mouse monoclonal antibody, clone 2704, Purified
Specifications
Product Data | |
Clone Name | 2704 |
Applications | IHC, WB |
Recommended Dilution | Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | Fusion protein of Human GPX7 |
Specificity | This antibody detects Glutathione Peroxidase 7 (GPX7). |
Formulation | PBS pH 7.4. without preservatives State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein G chromatography |
Storage | Store the antibody (in aliquots) at -20 °C to -70 °C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Human GPX7 is believed to be a member of the glutathione peroxidase family of proteins. These proteins play important roles in cellular defensemechanisms against oxidative damage. This isaccomplished by catalyzing the reduction ofhydroperoxides and hydrogen peroxide through thereducing substrate, glutathione. GPX7 protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. |
Synonyms | CL683, GSHPx-7 |
Reference Data |
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