FANCD2 Mouse Monoclonal Antibody [Clone ID: 103]

CAT#: AM06065PU-N

FANCD2 mouse monoclonal antibody, clone 103, Purified

Product Images

Formalin-Fixed Paraffin-Embedded Human Liver stained with FANCD2 antibody AM06065PU-N at 2.5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Clone Name: 103
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Human FANCD2 fusion protein.
• Specificity: Recognizes FANCD2.
• Formulation: PBS, pH 7.2 without preservatives.
  State: Purified
  State: Liquid purified Ig fraction.
• Purification: Protein G Chromatography.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 2177 Human
• Background: Fanconi Anemia Complementation Group D2 (FANCD2) protein is one of at least six factors shown to be involved in the autosomal-recessive cancer-prone disorder, Fanconi Anemia (FA). FA group D has been shown to be comprised of two separate proteins, FANCD1 and FANCD2. Mutations in BRCA2 can cause FANCD1. FANCD2 has been shown to colocalize with BRCA1 in ionizing radiation-induced foci. FANCD2 is involved in genomic resistance to DNA cross-linking reagents, and the arrest of DNA synthesis following exposure to ionizing radiation. FANCD2 has been shown to directly interact with NBS1.
• Synonyms: Fanconi anemia group D2 protein, FACD2, FACD
• Note: Predicted Molecular Weight: 176.5 kDa