Cd72 (CD72.1 alloantigen) Mouse Monoclonal Antibody [Clone ID: 10-1.D.2]

CAT#: AM08051BT-N

Cd72 (CD72.1 alloantigen) mouse monoclonal antibody, clone 10-1.D.2, Biotin

Specifications

Product Data

• Clone Name: 10-1.D.2
• Applications: FC
• Recommended Dilution: Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,2)
• Reactivities: Mouse
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: DBA/2 mouse spleen cells. (Ref.1)
• Specificity: This antibody recognises CD72.1/Lyb-2.1 (Mr. 45 kDa).
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  Label: Biotin
  State: Liquid purified Ig fraction.
• Concentration: 0.5 mg/ml
• Conjugation: Biotin
• Gene Name: CD72 antigen
• Database Link:
  Entrez Gene 12517 Mouse
• Background: Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (Ref.1,2)
  This clone blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (Ref.1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72. (Ref.1-5)
• Synonyms: Lyb-2, Ly-32, Ly32, B-Cell marker