Lamp2 Rat Monoclonal Antibody [Clone ID: ABL-93]

CAT#: AM08088PU-N

Lamp2 rat monoclonal antibody, clone ABL-93, Purified

Specifications

Product Data

• Clone Name: ABL-93
• Applications: FC, IHC, IP
• Recommended Dilution: Flow Cytometry: < / = 1 µg/10e6 cells.
  Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). (Ref.2,5)
  Immunoprecipitation. (Ref.2)
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Glycoproteins purified from BALB/c mouse embryo 3T3 cell line. (Ref.1)
• Specificity: This antibody is specific to CD107b/LAMP-2 (Mr 110-120 kDa with a core protein of Mr ~40 kDa).
• Formulation: 100 mM Borate Buffered Saline, pH 8.2.
  No preservatives or amine-containing buffer salts added.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: 0.5 mg/ml
• Database Link:
  Entrez Gene 16784 Mouse
• Background: CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. (Ref.1) CD107b is similar in structure to Mac-1 and is expressed primarily on epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. (Ref.2)
• Synonyms: LAMP-2, LAMP-2C, LAMPB