CD8A Mouse Monoclonal Antibody [Clone ID: fCD8]

CAT#: AM08112BT-N

CD8A mouse monoclonal antibody, clone fCD8, Biotin

Specifications

Product Data

• Clone Name: fCD8
• Applications: FC
• Recommended Dilution: Flow Cytometry: 1 µg/10e6 cells. (Ref.1-2)
  Immunohistochemistry on frozen tissue sections.
  Immunoprecipitation.
• Reactivities: Feline
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody recognizes Feline CD8 (Mr. 70 kDa) (38/31 kDa under reducing conditions).
• Formulation: PBS/NaN3
  Label: Biotin
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Conjugation: Biotin
• Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
• Synonyms: CD8 alpha chain, CD8A, MAL
• Note: U.S. Patent 4,520,110; European Patent No. 76,695; and Canadian Patent No. 1,179,942.
  FACScanTM is a registered trademark of Becton Dickinson Immunocytometry Systems, Inc., San Jose, CA.