CD4 Mouse Monoclonal Antibody [Clone ID: CT-4]

CAT#: AM08115BT-N

CD4 mouse monoclonal antibody, clone CT-4, Biotin

Specifications

Product Data

• Clone Name: CT-4
• Applications: FC
• Recommended Dilution: Flow Cytometry: ≤ 1 µg/10⁶ cells. (Ref.1)
• Reactivities: Chicken
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Chicken thymocytes and Ig-negative blood leukocytes.
• Specificity: Specific to CD4 (Mr. 64 kda).
  This antibody inhibits both PHA- and Con A-induced proliferative responses of splenocytes, and PWM-induced IL-2 production.
• Formulation: PBS containing 0.09% Sodium Azide as preservative
  Label: Biotin
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Conjugation: Biotin
• Background: CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
• Synonyms: T-cell surface antigen T4/Leu-3