LOC396098 Mouse Monoclonal Antibody [Clone ID: 21-1A4]
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Specifications
Product Data | |
Clone Name | 21-1A4 |
Applications | FC |
Recommended Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1) |
Reactivities | Chicken |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Bursal cells from one-day-old H.B15 (Bu-1a/b) strain chickens. |
Specificity | This antibody recognizes Chicken Bu-1a alloantigen (Mr. 70 kDa). It does not react with cells from CHA and H.B15 strains by Immunofluorescence. |
Formulation | PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction. |
Concentration | 0.5 mg/ml |
Conjugation | Biotin |
Gene Name | B6.1 |
Database Link | |
Background | Chicken Bu-1a, a product of the Bu-1a allele, is expressed on the cell surface as a disulfide-linked homodimer. In 10-week-old H.B15 and H.B2 chickens, Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes, but not on granulocytes, erythrocytes or thrombocytes. In Chickens heterozygous for the Bu-1 alleles (Bu-1a/b), Bu-1a does not exhibit allelic exclusion. |
Synonyms | B-Cell Marker |
Reference Data |
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