VSIG1 Mouse Monoclonal Antibody [Clone ID: CT1]

CAT#: AM08142BT-N

VSIG1 mouse monoclonal antibody, clone CT1, Biotin

Specifications

Product Data

• Clone Name: CT1
• Applications: FC
• Recommended Dilution: Flow Cytometry: < / = 1 µg/10e6 cells.
  Identification and enumeration of ChT1+ cells. (Ref.4)
• Reactivities: Chicken
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Chicken thymocytes.
• Specificity: This antibody is specific to ChT1 antigen (Mr 63/104 kDa) on Chicken thymocyte. (Ref.1)
  CT1 can block T cell differentiation in vitro, in thymic organ cultures and in thymocyte precursors cultured on stromal cell monolayers. (Ref.4)
  CT1 also recognizes quail cortical thymocytes. (Ref.1)
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  Label: Biotin
  State: Liquid purified Ig fraction.
• Concentration: 0.5 mg/ml
• Conjugation: Biotin
• Gene Name: V-set and immunoglobulin domain containing 1
• Database Link:
  Entrez Gene 414795 Chicken
• Background: ChT1, a member of the Ig superfamily with one V-like and one C2-like domain, is a T cell antigen that is expressed on the surface of embryonic thymocytes (day 10). In young chickens, about 90% of the thymocytes as well as a subpopulation of peripheral lymphocytes (which represent recent thymic emigrants) are ChT1 positive. (Ref.1-4) Expression in the periphery declines with age and, in correlation with partial thymectomy, indicates that ChT1 can be used as an accurate marker for studying thymic function. (Ref.3)
• Synonyms: Cell surface A33 antigen, Glycoprotein A34, GPA34