T Cell Receptor (TCR) alpha/beta Mouse Monoclonal Antibody [Clone ID: IP26]

CAT#: AM26003BT-N

T Cell Receptor (TCR) alpha/beta mouse monoclonal antibody, clone IP26, Biotin

Specifications

Product Data

• Clone Name: IP26
• Applications: FC
• Recommended Dilution: Indirect immunofluorescence analysis by Flow cytometry: 1:300.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: The antibody recognizes a monomorphic determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood.
• Formulation: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
  Label: Biotin
  State: Liquid purified Ig fraction
  Label: Conjugated with -LC-NHS under optimum conditions. The reagent is free of unconjugated biotin
• Concentration: 1.0 mg/ml
• Conjugation: Biotin
• Background: The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.