CD82 Mouse Monoclonal Antibody [Clone ID: C33]
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Specifications
Product Data | |
Clone Name | C33 |
Applications | FC |
Recommended Dilution | Indirect immunofluorescence analysis by Flow cytometry. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | C91/PL (human HTLV-1+ T cell line) |
Specificity | This antibody reacts with CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments. |
Formulation | Phosphate buffered saline (PBS) Label: Biotin State: Liquid purified Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4 Label: Conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin. |
Concentration | lot specific |
Conjugation | Biotin |
Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated. |
Synonyms | KAI1, SAR2, ST6, TSPAN27, C33 antigen, IA4, Kangai-1, Tetraspanin-27 |
Reference Data |
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