RCC1 Mouse Monoclonal Antibody [Clone ID: 2F1]

CAT#: AM31738PU-N

RCC1 mouse monoclonal antibody, clone 2F1, Purified

Product Images

Western Blot analysis of RCC1 expression in A-431 cell lysate.

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  Western Blot analysis of RCC1 expression in transfected 293T cell line. Lane 1: RCC1 transfected lysate (45 KDa). Lane 2: Non-transfected lysate.

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  Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence of monoclonal antibody to RCC1 on HeLa cell at 10 mg/ml.

Specifications

Product Data

• Clone Name: 2F1
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: RCC1 antibody was raised against RCC1 (AAH07300, 312 a.a. ~ 421 a.a) partial recombinant protein with GST tag.
• Specificity: Recognizes RCC1 / CHC1.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody (in aliquots) at -20°C or -80°C.
  Avoid freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens regulator of chromosome condensation 1 (RCC1), transcript variant 1
• Database Link:
  Entrez Gene 1104 Human
• Background: RCC1 promotes the exchange of Ran-bound GDP by GTP. It is involved in the regulation of onset of chromosome condensation in the S phase. RCC1 binds to chromatin. The RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Patients with Raynaud disease produce antibodies that bind to RCC1.
• Synonyms: RCC1-I