Cezanne (OTUD7B) Mouse Monoclonal Antibody [Clone ID: 2B4]

CAT#: AM31751PU-N

Cezanne (OTUD7B) mouse monoclonal antibody, clone 2B4, Purified

Product Images

Detection limit for recombinant GST tagged OTUD7B is 0.3 ng/ml as a capture antibody.

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  Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 2B4
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: OTUD7B antibody was raised against amino acids 744 to 843 of NP_064590, with a GST tag.
• Specificity: Recognizes OTUD7B/Cezanne.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 0.42 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens OTU deubiquitinase 7B (OTUD7B)
• Database Link:
  Entrez Gene 56957 Human
• Background: OTUD7B has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.
  OTUD7B is Widely expressed. Abundant in kidney, heart and fetal liver. Expressed differentially among B-cells at distinct developmental stages. Higher expression seen in primary immature B-cells as compared to the mature cells.
  Sequence similarities:
  Belongs to the peptidase C64 family.
  Contains 1 A20-type zinc finger.
  Contains 1 OTU domain.
• Synonyms: OTUD7B, Cezanne