MHC Class I H-2 Kk Mouse Monoclonal Antibody [Clone ID: H100-5/28]
CAT#: AM31876BT-N
MHC Class I H-2 Kk mouse monoclonal antibody, clone H100-5/28, Biotin
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Specifications
Product Data | |
Clone Name | H100-5/28 |
Applications | FC |
Recommended Dilution | Flow Cytometry. |
Reactivities | Mouse |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Specificity | This Monoclonal Antibody specifically reacts with the H-2Kk (Determinant H-2.m11) encoded MHC Class I antigen expressed on mouse strains of the H-2k haplotype. This antibody is also reported to react with H-2Kq and H-2r haplotypes. Class I antigens are expressed on all nucleated cells. |
Formulation | PBS containing 0.02% Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml Label: Biotin State: Liquid purified Ig fraction |
Concentration | 0.1 mg/ml |
Purification | Protein G Chromatography |
Conjugation | Biotin |
Background | MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta2- microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. Lymphocytes are highly positive whereas fibroblasts or neurons show only a low level of antigen. |
Synonyms | H2-K1, H2-K, H-2K(K) |
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