MRP4 (ABCC4) Rat Monoclonal Antibody [Clone ID: M4I-10]

CAT#: AM32023SU-N

MRP4 (ABCC4) rat monoclonal antibody, clone M4I-10, Supernatant

Specifications

Product Data

• Clone Name: M4I-10
• Applications: IF, IHC, WB
• Recommended Dilution: Western blotting: Use at 1/20-1/50 dilution and anti-Rat-HRP.
  Immunocytochemistry: Use at 1/20 on Acetone Fixed Cytospin preparations.
  Immunohistochemisty on Frozen Sections: 1/20 on Acetone Fixed Frozen sections can be followed by incubation with Biotin conjugated Rabbit anti-Rat IgG (1/100) and and HRP-labeled Streptavidin (1/ 500).
• Reactivities: Human
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: A fusion protein containing the E. coli maltose binding protein and a fragment of the human MRP4 protein corresponding to amino acids 372-431.
• Specificity: This Monoclonal antibody clone M4I-10 recognizes MRP4/ABCC4.
  The M4I-10 Mab also reacts with the Mouse orthologue of the transporter molecule (Mrp4).
• Formulation: State: Supernatant
  State: Serum Free Culture Supernatant
  Stabilizer: 0.7% BSA
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: ATP binding cassette subfamily C member 4
• Database Link:
  Entrez Gene 10257 Human
• Background: ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions.
• Synonyms: Multidrug resistance-associated protein 4, MOAT-B