Bone Sialoprotein (IBSP) Goat Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA, R |
Recommended Dilution | ELISA. RIA. |
Reactivities | Human |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Rec. human Bone Sialoprotein |
Specificity | This antibody detects Bone Sialoprotein. |
Formulation | State: Serum State: Lyophilized serum |
Reconstitution Method | Restore in aqua bidest to initial volume. |
Gene Name | integrin binding sialoprotein |
Database Link | |
Background | The protein encoded by the Bone Sialoprotein gene is a major structural protein of the bone matrix. It is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts, and it constitutes approximately 12% of the noncollagenous proteins in human bone. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. |
Synonyms | Bone sialoprotein II, BSP II, IBSP, BNSP |
Note | LocusID 3381 |
Reference Data |
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