CGRP (CALCB) Goat Polyclonal Antibody
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Specifications
Product Data | |
Applications | R |
Recommended Dilution | RIA (1/3,000). |
Reactivities | Human |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Synthetic Human Calcitonin Gene-related Peptide 2, bTG-conjugated |
Specificity | This antibody detects Calcitonin Gene-related Peptide. There were no cross reactivities obtained with Human and Salmon Katacalcin and Calcitonin. |
Formulation | State: Serum State: Lyophilized serum |
Reconstitution Method | Restore in aqua bidest to initial volume. |
Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed. |
Synonyms | Calcitonin gene-related peptide 2, Beta-type CGRP, CALC2 |
Note | LocusID: 797 |
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