SHP2 (PTPN11) (C-term) Rabbit Polyclonal Antibody
Other products for "PTPN11"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/50 - 1/100. |
Reactivities | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide selected from the C-terminal region of human PTPN11 |
Specificity | This antibody reacts to PTPN11. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Liquid purified Ig |
Concentration | lot specific |
Purification | Saturated Ammonium Sulfate (SAS) precipitation |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant 1 |
Database Link | |
Background | PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic ansformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. |
Synonyms | SHPTP2, PTP-1D, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3 |
Reference Data | |
Protein Families | Druggable Genome, Phosphatase |
Protein Pathways | Adipocytokine signaling pathway, Chronic myeloid leukemia, Epithelial cell signaling in Helicobacter pylori infection, Jak-STAT signaling pathway, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Renal cell carcinoma |
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