NKG2A (KLRC1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP18087PU-N

NKG2A (KLRC1) (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of KLRC1 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). KLRC1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-term region of human KLRC1.
• Specificity: This antibody reacts to KLRC1 / CD159a.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 1
• Database Link:
  Entrez Gene 3821 Human
• Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.
• Synonyms: KLRC1, NKG2A, NKG2-A/B-activating NK receptor, NK cell receptor A, CD159 antigen-like family member A, CD159a

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Antigen processing and presentation, Graft-versus-host disease, Natural killer cell mediated cytotoxicity