VGF (C-term) Rabbit Polyclonal Antibody

CAT#: AP22596PU-N

VGF (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with VGF antibody at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 0.5 - 1 µg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: 17 amino acid peptide near the carboxy terminus of the human VGF
• Specificity: This antibody detects Human VGF (C-term).
  The immunogen is after amino acid 577 of O15240, so the antibody should only cross-react with full-length VGF and none of the processed peptides.
• Formulation: PBS, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens VGF nerve growth factor inducible (VGF)
• Database Link:
  Entrez Gene 29461 RatEntrez Gene 381677 MouseEntrez Gene 7425 Human
• Background: VGF encodes a 70-kD polypeptide that shares similarities with the secretogranin/ chromogranin family and is found in the secretory granules of subsets of neurons and endocrine cells. Expression of VGF is both developmentally regulated and in regulated in different brain regions in response to different stimuli. VGF has been shown to play a role in energy homeostasis. Expression of VGF in the hypothalamus of rats and mice is induced by exercise and in response to fasting.
• Synonyms: Neurosecretory protein VGF

Reference Data

• Protein Families: Secreted Protein