GABA A Receptor beta 1 (GABRB1) (1-226) Rabbit Polyclonal Antibody

CAT#: AP23606PU-N

GABA A Receptor beta 1 (GABRB1) (1-226) rabbit polyclonal antibody, Aff - Purified

Product Images

Sample (30g whole cell lysate). A: 293T. B: A431. C: H1299. D: HeLa S3. E: Hep G2. F: MOLT4. G: Raji. 10% SDS PAGE. GABRB1 antibody diluted at 1/1000

• 

  Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/500 - 1/3000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 226 of Human GABA A Receptor beta 1
• Specificity: This antibody detects Human GABA A Receptor beta 1 at aa 1-226.
• Formulation: 0.1 M Tris-glycine, pH 7.0 containing 10% Glycerol and 0.01% Thimerosal
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody (in aliqouts) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens gamma-aminobutyric acid type A receptor beta1 subunit (GABRB1)
• Database Link:
  Entrez Gene 14400 MouseEntrez Gene 25450 RatEntrez Gene 2560 Human
• Background: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
• Synonyms: GABRB-1, GABA A receptor subunit beta-1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction