CCR4 Rabbit Polyclonal Antibody

CAT#: AP26357PU-N

CCR4 rabbit polyclonal antibody, Aff - Purified

Product Images

: Western blot analysis of CCR4 using Jurkat cell lysates.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot (2-6 µg/ml).
• Reactivities: Canine, Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 32 of human CCR4
• Specificity: This antibody detects CCR4 surrounding amino acid 32.
• Formulation: Phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: Homo sapiens C-C motif chemokine receptor 4 (CCR4)
• Database Link:
  Entrez Gene 12773 MouseEntrez Gene 1233 Human
• Background: CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine.
• Synonyms: C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CMKBR4, K5-5

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction