EVC2 (1296-1308) Goat Polyclonal Antibody

CAT#: AP31073PU-N

EVC2 (1296-1308) goat polyclonal antibody, Aff - Purified

Product Images

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/16000.
  Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from the C-terminus of human EVC2 (NP_667338.3; NP_001159608.1)
• Specificity: This antibody recognizes EVC2 (C-term).
  It is expected to recognise isoform 1 (NP_667338.3) and isoform 2 (NP_001159608.1).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified IgG fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens EvC ciliary complex subunit 2 (EVC2), transcript variant 2
• Database Link:
  Entrez Gene 132884 Human
• Background: EVC2 is a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities.
• Synonyms: EVC2, LBN

Reference Data

• Protein Families: Transmembrane