MMP11 (61-110) Rabbit Polyclonal Antibody

CAT#: AP31345PU-N

MMP11 (61-110) rabbit polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ul

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Specifications

Product Data
Applications ELISA, IF, IHC, WB
Recommended Dilution ELISA: 1/20000.
Immunofluorescence: 1/100 - 1/500.
Immunohistochemistry on Paraffin Sections: 1/100.
Western Blot: 1/500 - 1/1000.
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide from Human MMP-11 (aa61-110)
Specificity This antibody detects endogenous levels of total MMP-11 protein (aa61-110).
Formulation PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol
State: Aff - Purified
State: Liquid purified IgG fraction
Purification Immunoaffinity Chromatography
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens matrix metallopeptidase 11 (MMP11), transcript variant 1
Background MMP11, also known as stromelysin 3, is overexpressed in the stromal cells of invasive breast carcinomas but not in the stromal cells surrounding benign breast fibroadenomas. MMP11 is secreted in its proenzyme from and the zymogen has a mass of 64 kDa. The enzyme is rapidly activated to a 58 kDa form, a 45-47 kDa size, then to a 28 kDa final active form. MMP11 is not constitutively produced by most cell types. It has been found in lung fibroblasts and gingival fibroblasts when stimulated with EGF, as well as breast tumor and osteocarcinoma cell lines.
Synonyms MMP11, Stromelysin-3, SL-3, ST3, STMY3, Matrix metalloproteinase-11
Reference Data
Protein Families Druggable Genome, Protease

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.