Ancient ubiquitous protein 1 (AUP1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP50315PU-N

Ancient ubiquitous protein 1 (AUP1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

AUP1 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the AUP1 antibody detected the AUP1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/.500
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 439-468 amino acids from the C-terminal region of human AUP1
• Specificity: This antibody reacts to AUP1.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ancient ubiquitous protein 1 (AUP1), transcript variant 2
• Database Link:
  Entrez Gene 550 Human
• Background: This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.
• Synonyms: Ancient ubiquitous protein 1
• Note: Molecular Weight: 53028 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane