CTBP1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51115PU-N

CTBP1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

CTBP1 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CTBP1 antibody detected the CTBP1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 412-442 amino acids from the C-terminal region of human CTBP1
• Specificity: This antibody reacts to human and mouse CTBP1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 47535 Da
• Gene Name: Homo sapiens C-terminal binding protein 1 (CTBP1), transcript variant 2
• Database Link:
  Entrez Gene 13016 MouseEntrez Gene 1487 Human
• Background: This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
• Synonyms: C-terminal-binding protein 1, CTBP

Reference Data

• Protein Pathways: Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway