DOK3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51307PU-N

DOK3 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of DOK3 Antibody (C-term) in CEM cell line lysates (35ug/lane). This demonstrates the DOK3 antibody detected the DOK3 protein (arrow).

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  Formalin fixed and paraffin embedded human lung tissue reacted with DOK3 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 300-329 amino acids from the C-terminal region of Human DOK3
• Specificity: This antibody recognizes Human DOK3 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Gene Name: Homo sapiens docking protein 3 (DOK3), transcript variant 2
• Database Link:
  Entrez Gene 79930 Human
• Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function (By similarity).
• Synonyms: Docking protein 3
• Note: Molecular Weight: 53288 Da

Reference Data

• Protein Families: Druggable Genome