Dematin (DMTN) (Center) Rabbit Polyclonal Antibody

CAT#: AP51441PU-N

Dematin (DMTN) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Dematin Antibody in Y79 cell line lysates (35ug/lane). This demonstrates the Dematin antibody detected the Dematin protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 248-277 amino acids from the Central region of Human Dematin.
• Specificity: This antibody recognizes Human Dematin (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens dematin actin binding protein (DMTN), transcript variant 2
• Database Link:
  Entrez Gene 2039 Human
• Background: Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).
• Synonyms: EPB49, DMT
• Note: Molecular Weight: 45514 Da