Gephyrin (GPHN) (Center) Rabbit Polyclonal Antibody
Other products for "GPHN"
Specifications
Product Data | |
Applications | FC, IHC, WB |
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100. Flow Cytometry: 1/10 - 1/50. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 444~474 amino acids from the Central region of human GPHN |
Specificity | This antibody reacts to GPHN. |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 79748 Da |
Gene Name | Homo sapiens gephyrin (GPHN), transcript variant 2 |
Database Link | |
Background | GPHN encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. |
Synonyms | GPHN, GPH, KIAA1385 |
Reference Data | |
Protein Families | Druggable Genome |
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