GPR34 (Center) Rabbit Polyclonal Antibody

CAT#: AP51926PU-N

GPR34 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in MDA-MB231 cell line lysates (35ug/lane) using GPR34 antibody. This demonstrates the GPR34 antibody detected the GPR34 protein (arrow).

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  Immunohistochemistry analysis in human liver tissue (formalin-fixed, paraffin-embedded) using GPR34 antibody., followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GPR34 antibody for IHC. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  This antibody is suitable for immunohistochemistry on paraffin sections and Western blotting.
  The suggested dilution is:
  Immunohistochemistry on paraffin sections: 1/10-1/50.
  Western blotting: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 239-269aa) of human GPR34.
• Specificity: This antibody detects human GPR34.
• Formulation: PBS with 0.09% (W/V) Sodium Azide.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column; followed by peptide affinity purification.
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens G protein-coupled receptor 34 (GPR34), transcript variant 4
• Database Link:
  Entrez Gene 2857 Human
• Background: G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.
• Synonyms: G-protein coupled receptor 34
• Note: Molecular Weight: 43860 Da

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane