IRAK4 (N-term) Rabbit Polyclonal Antibody
Other products for "IRAK4"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 32-60 amino acids from the N-terminal region of Human IRAK4. |
Specificity | This antibody recognizes Human IRAK4 (N-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens interleukin 1 receptor associated kinase 4 (IRAK4), transcript variant 1 |
Database Link | |
Background | This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms | IRAK-4, NY-REN-64 |
Note | Molecular Weight: 51530 Da |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Apoptosis, Neurotrophin signaling pathway, Toll-like receptor signaling pathway |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.