MAD1 (MAD1L1) (N-term) Rabbit Polyclonal Antibody

CAT#: AP52579PU-N

MAD1 (MAD1L1) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of MAD1L1 Antibody (N-term) in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the MAD1L1 antibody detected the MAD1L1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 131-159 amino acids from the N-terminal region of human MAD1L1
• Specificity: This antibody recognizes Human MAD1L1 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 2
• Database Link:
  Entrez Gene 8379 Human
• Background:
  MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
• Synonyms: Mitotic spindle assembly checkpoint protein MAD1, MAD1-like 1
• Note: Molecular Weight: 83067 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle