NUP50 (Center) Rabbit Polyclonal Antibody

CAT#: AP52974PU-N

NUP50 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of NUP50 Antibody (Center) in WiDr cell line lysates (35ug/lane). This demonstrates the NUP50 antibody detected the NUP50 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human NUP50.
• Specificity: This antibody recognizes Human NUP50 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens nucleoporin 50 (NUP50), transcript variant 2
• Database Link:
  Entrez Gene 10762 Human
• Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: Nucleoporin 50 kDa, NPAP60L
• Note: Molecular Weight: 50144 Da

Reference Data

• Protein Families: Stem cell - Pluripotency