RNF70 (PJA1) (N-term) Rabbit Polyclonal Antibody
Other products for "PJA1"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. Immunohistochemistry on Paraffin Sections: 1/10-1/50. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human PJA / RNF70 |
Specificity | This antibody recognizes Human PJA1 / RNF70 (N-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens praja ring finger ubiquitin ligase 1 (PJA1), transcript variant 3 |
Database Link | |
Background | This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. |
Synonyms | Praja1, Praja-1, RING finger protein 70 |
Note | Molecular Weight: 71002 Da |
Reference Data | |
Protein Families | Druggable Genome |
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