RbAp46 (RBBP7) (Center) Rabbit Polyclonal Antibody

CAT#: AP53600PU-N

RbAp46 (RBBP7) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of RBBP7 / RBAP46 Antibody in CEM cell line lysates (35ug/lane). This demonstrates the RBBP7 antibody detected the RBBP7 protein (arrow).

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  Western blot analysis of RBBP7 (arrow) using RBBP7 / RBAP46 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RBBP7 gene.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of Human RBBP7.
• Specificity: This antibody recognizes Human RBBP7 (Center).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 2
• Database Link:
  Entrez Gene 5931 Human
• Background:
  This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: RBBP-7
• Note: Molecular Weight: 47820 Da

Reference Data

• Protein Families: Druggable Genome