Gnao1 (345-354) Rabbit Polyclonal Antibody

CAT#: BP932

Gnao1 (345-354) rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA (1/100K - 1/400K).
  Western blot (gives a band at 39 kDa when used under reducing conditions against rat brain).
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to the amino acids 345 - 354 of the native molecule conjugated to Keyhole Limpet Haemocyanin
• Specificity: This antibody detects G Protein-alpha 0.
• Formulation: PBS , pH 7.2, 0.09 % Sodium Azide
  State: Purified
  State: Liquid Ig fraction
• Concentration: 2.4 mg/ml (lot spec.)
• Purification: Ammonium Sulphate fractionation
• Gene Name: Mus musculus guanine nucleotide binding protein, alpha O (Gnao1), transcript variant B
• Database Link:
  Entrez Gene 14681 Mouse
• Background: GTP binding proteins (G proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Go belongs to the pertussis toxin sensitive G proteins. It consists of two subtypes of a subunits (ao1 and ao2) derived from alternative splicing of a single gene. ao1 differs from ao2 within the C terminal.
• Synonyms: Gnao1, Gna0, Gnao