Birch Pollen (allergen Bet v1) Mouse Monoclonal Antibody [Clone ID: 202B8.03]

CAT#: DDX0052P-100

Birch Pollen (allergen Bet v1) mouse monoclonal antibody, clone 202B8.03

Product Images

Modulation of IgE (allergic patients) binding to Bet v 1

• 

  Cross-reactivity with Bet v 1 homologous plant allergens

• 

  mAbs binding to nitrocellulose-blotted natural (n) or recombinant birch pollen Bet v 1

• 

  Single-step immunopurification of natural Bet v 1 using mAb7

Specifications

Product Data

• Clone Name: 202B8.03
• Applications: NEUT
• Recommended Dilution: Binding to nitrocellulose-blotted Bet v 1, inhibition of human IgE binding to Bet v1, cross-competition with anti-Bet v1 mAbs, Bet v1 immunoprecipitation.
  Usage recommendation: *This monoclonal antibody may be used between 5-20 μg/ml.
  
• Reactivities: Pollen
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: pollen grains from Betula alba
• Specificity: Birch pollen Bet v 1
  Cross-reactivity: Bet v 1 homologous plant allergens.
• Formulation: State: Purified
  State: 100 μg in 200 μl Tris-NaCl pH 8
• Concentration: 0.5 mg/ml
• Purification: QMA Hyper-D Ion-exchange chromatography
• Background: Bet v 1 and homologous proteins represent major allergens for almost 95% of patients allergic to tree pollen and approximately 70% of those allergic to fruits and vegetables. Birch pollen allergy is a frequent pathology with IgE reactivity against Bet v 1. A panel of 85 mouse monoclonal anti-Bet v 1 antibodies was raised as a tool to study the interaction of human IgE antibodies with Bet v 1. Cross-reactivities with Bet v 1 homologous plant allergens, modulation of IgE binding to Bet v 1, Bet v 1 immunopurification, and inhibition of histamine release are described in the original article.
  (Lebecque S et l, J Allergy Clin Immunol, 1997; 99:374-84).