PROX1 (C-term) Rabbit Polyclonal Antibody

CAT#: DP3516B

PROX1 (C-term) rabbit polyclonal antibody, Biotin

Specifications

Product Data

• Applications: IF
• Recommended Dilution: Immunofluorescence: 1-5 µg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant highly conserved C-terminal part of the homeobox transcription factor Human Prox1 (homeo domain and prospero domain) (Cat.-No DA3565).
• Specificity: This antibody will detect Prox-1 in the nucleus of lymphatic endothelial cells.
• Formulation: 5mM PBS, pH 7.2
  Label: Biotin
  State: Lyophilized purified IgG fraction
  Stabilizer: 50X BSA
  Preservative: 0.02% Sodium Azide
• Reconstitution Method: Restore in sterile water to a concentration of 0.1-1.0 mg/ml
• Purification: Antigen Affinity Chromatography
• Conjugation: Biotin
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens prospero homeobox 1 (PROX1), transcript variant 2
• Database Link:
  Entrez Gene 19130 MouseEntrez Gene 305066 RatEntrez Gene 5629 Human
• Background: Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells.
• Synonyms: PROX1

Reference Data

• Protein Families: Embryonic stem cells, ES Cell Differentiation/IPS