Cd19 Rat Monoclonal Antibody [Clone ID: 6D5]
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Specifications
Product Data | |
Clone Name | 6D5 |
Applications | FC |
Recommended Dilution | Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human K562 cell line transfected with murine CD19. Spleen cells from immunised rats were fused with cells of the P3X63.Ag8.653 myeloma cell line. |
Specificity | This antibody recognises the CD19 cell surface antigen, a 95kD glycoprotein expressed by B lymphocytes. Clone 6D5 has been shown to recognise the same epitope as clone ID3 in cross-competition assays. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: Biotin State: Liquid purified IgG fraction. |
Concentration | 0.1 mg/ml |
Purification | Affinity Chromatography on Protein G. |
Conjugation | Biotin |
Database Link | |
Background | CD19 is a 95 kD glycoprotein, also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81 forms a molecular complex integral to B cell activation. |
Synonyms | Leu-12, B-cell marker |
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