CD9 Mouse Monoclonal Antibody [Clone ID: MM2/57]

CAT#: SM1065B

CD9 mouse monoclonal antibody, clone MM2/57, Biotin

Product Images

Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD9:BIOTIN

Specifications

Product Data

• Clone Name: MM2/57
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10µl of Neat-1/5 diluted antibody to label 10e6 cells or 100µl whole blood.
• Reactivities: Bovine, Canine, Equine, Feline, Human, Rabbit
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Human platelet membrane. Spleen cells from BALB/c mice immunised were fused with cells of the mouse SP2/0 myeloma line.
• Specificity: This antibody recognises CD9, a 24kD surface glycoprotein expressed by platelets, monocytes, some lymphocytes and endothelial cells.
• Formulation: Contains 0.09% Sodium Azide as preservative and 1% Bovine Serum Albumin as stabilizer.
  Label: Biotin
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Biotin
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 928 Human
• Background: CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.
• Synonyms: MIC3, TSPAN29, GIG2, p24, Tetraspanin-29, 5H9 antigen