CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: LNK16]
Specifications
Product Data | |
Clone Name | LNK16 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Neat-1/5; Use 10µl of the suggested working dilution to label 10e6 cells or 100 µl human whole blood. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Normal human peripheral blood granulocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line. |
Specificity | This antibody recognises CD16. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% Bovine Serum Albumin as stabilizer. Label: Biotin State: Liquid purfied IgG fraction. |
Concentration | lot specific |
Purification | Ion Exchange Chromatography |
Conjugation | Biotin |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CD16 is a 50-65kD cell surface molecule which exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. |
Synonyms | FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2 |
Reference Data |
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