FLIP (CFLAR) (Long Form) (C-term) Rabbit Polyclonal Antibody
Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | Western blot: 1/500 - 1/2000. Immunocytochemistry. |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide at C-terminus of human FLIPL |
Specificity | This antibody recognises the 55kD FLIPL protein, a FLICE inhibitory protein. |
Formulation | PBS containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG |
Concentration | 0.5 mg/ml |
Purification | Ion exchange chromatography |
Database Link | |
Background | FLIP was cloned independently in a number of laboratories, and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors. FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognised by this antibody. |
Synonyms | c-FLIP, CLARP, MRIT, CASH, FLAME-1, CASP8AP1, Usurpin |
Reference Data |
Documents
Product Manuals |
FAQs |
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