XRCC3 Mouse Monoclonal Antibody [Clone ID: 10F1/6]

CAT#: TA301487

Mouse Monoclonal Antibody against XRCC3 (10F1/6)

Product Images

XRCC3 detected in HEK293 lysates using a 1:1,000 dilution

Specifications

Product Data

• Clone Name: 10F1/6
• Applications: WB
• Recommended Dilution: WB: 1: 1000
• Reactivities: Human, not Mouse
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: His-tagged human XRCC3, over-expressed in E. coli
• Formulation: PBS, pH 7.4, 0.1% sodium azide
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 3
• Database Link:
  NP_005423
  Entrez Gene 74335 MouseEntrez Gene 7517 Human
  UniProt ID O43542
• Background: Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homologs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes. XRCC3 (x-ray cross complementing) was first identified as a human gene complementing the DNA damage sensitivity, chromosonal instability and impaired growth of the mutant hamster cell line irs1SF. This fact coupled with XRCC3 being a member of the RAD51 gene family have implied a role in the repair of DNA damage by homologous recombination.
• Synonyms: CMM6

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Homologous recombination