ORAI2 Rabbit Polyclonal Antibody
Other products for "ORAI2"
Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | WB: 1 - 4 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | ORAI2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ORAI2. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | Affinity chromatography purified via peptide column |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | ORAI calcium release-activated calcium modulator 2 |
Database Link | |
Background | Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3. |
Synonyms | C7orf19; CBCIP2; MEM142B; TMEM142B |
Reference Data | |
Protein Families | Transmembrane |
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