REEP4 Rabbit Polyclonal Antibody

CAT#: TA306910

Rabbit Polyclonal REEP4 Antibody

Product Images

Western blot analysis of REEP4 in human lung tissue lysate with REEP4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: REEP4 antibody was raised against a 17 amino acid peptide near the center of human REEP4.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: receptor accessory protein 4
• Database Link:
  NP_079508
  Entrez Gene 72549 MouseEntrez Gene 306014 RatEntrez Gene 80346 Human
  UniProt ID Q9H6H4
• Background: Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression. Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members. In studies in Xenopus RNAi to reduce REEP4 levels, embryos showed a slightly kinked body axis and were paralyzed. Further analysis revealed downregulated levels of several neural and muscle markers, suggesting the REEP4 may play a role in the maintenance of both the nervous system and musculature.
• Synonyms: C8orf20; PP432; Yip2c

Reference Data

• Protein Families: Druggable Genome, Transmembrane