CMAS Rabbit Polyclonal Antibody

CAT#: TA308566

Rabbit polyclonal antibody to CMAS (cytidine monophosphate N-acetylneuraminic acid synthetase)

Product Images

Sample (30 ug of whole cell lysate). A:293T. B:HeLa S3. 7.5% SDS PAGE. TA308566 diluted at 1:1500

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  Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using CMAS (TA308566) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 69 and 414 of CMAS (Uniprot ID#Q8NFW8)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 48 kDa
• Gene Name: cytidine monophosphate N-acetylneuraminic acid synthetase
• Database Link:
  NP_061156
  Entrez Gene 55907 Human
• Background: The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus. [provided by RefSeq]
• Synonyms: CSS
• Note: Seq homology of immunogen across species: Rhesus Monkey (100%)

Reference Data

• Protein Pathways: Amino sugar and nucleotide sugar metabolism, Metabolic pathways