Nefl Mouse Monoclonal Antibody [Clone ID: DA2]

CAT#: TA309178

Mouse Anti-Neurofilament NF-L ms Antibody

Product Images

Western blot of rat cortex lysate showing specific immunolableing of the ~ 68k NF-L protein.

Specifications

Product Data

• Clone Name: DA2
• Applications: WB
• Recommended Dilution: WB: 1:1,000, IF: 1:100
• Reactivities: Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Preparation of porcine NF-L
• Formulation: total IgG fraction + 10 mM NaN3.
• Purification: Total IgG fraction
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 68 kDa
• Gene Name: neurofilament, light polypeptide
• Database Link:
  NP_113971
  Entrez Gene 83613 Rat
  UniProt ID P19527
• Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq]
• Synonyms: CMT1F; CMT2E; FLJ53642; neurofilament-light; NF-L; NF68; NFL