MMP11 Rabbit Polyclonal Antibody

CAT#: TA318918

Rabbit polyclonal anti-MMP-11 antibody

Product Images

Western blot analysis of MMP-11 in Jurkat cell lysate (Lane 1& 2).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 464 of mouse MMP-11
• Formulation: 100 µg (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: matrix metallopeptidase 11
• Database Link:
  NP_005931
  Entrez Gene 17385 MouseEntrez Gene 25481 RatEntrez Gene 4320 Human
  UniProt ID P24347
• Background: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. The antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11 from human, mouse, and rat origins.
• Synonyms: SL-3; ST3; STMY3

Reference Data

• Protein Families: Druggable Genome, Protease