SLAMF1 Rabbit Polyclonal Antibody

CAT#: TA319706

Rabbit Polyclonal SLAMF1 Antibody

Product Images

Western blot analysis of SLAMF1 in rat colon tissue lysate with SLAMF1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of SLAMF1 in human colon tissue with SLAMF1 antibody at 5 ug/mL.

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  Immunofluorescence of SLAMF1 in human colon tissue with SLAMF1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SLAMF1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SLAMF1.
• Formulation: SLAMF1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SLAMF1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: signaling lymphocytic activation molecule family member 1
• Database Link:
  NP_003028
  Entrez Gene 27218 MouseEntrez Gene 498286 RatEntrez Gene 6504 Human
  UniProt ID Q13291
• Background: SLAMF1 Antibody: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).
• Synonyms: CD150; CDw150; SLAM

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane