RUSC2 Rabbit Polyclonal Antibody

CAT#: TA319795

Rabbit Polyclonal RUSC2 Antibody

Product Images

Western blot analysis of RUSC2 in SK-N-SH cell lysate with RUSC2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide

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  Immunohistochemistry of RUSC2 in human brain tissue with RUSC2 antibody at 5 ug/mL.

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  Immunofluorescence of RUSC2 in human brain tissue with RUSC2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: RUSC2 antibody was raised against an 18 amino acid synthetic peptide from near the amino terminus of human RUSC2.
• Formulation: RUSC2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: RUSC2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: RUN and SH3 domain containing 2
• Database Link:
  NP_055621
  Entrez Gene 100213 MouseEntrez Gene 9853 Human
  UniProt ID Q8N2Y8
• Background: RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
• Synonyms: Iporin